Product Description
Product Name: Xvir Tablet
Active Ingredient: Entecavir
Strength: 0.5 mg
Form: Oral Tablet
Manufacturer & Marketer: Natco Pharma Ltd.
Category: Antiviral Agent
Indication: Chronic Hepatitis B Virus (HBV) Infection
Xvir 0.5 mg Tablet contains Entecavir, a potent antiviral medication used in the treatment of chronic Hepatitis B virus (HBV) infection in adults with evidence of active viral replication and liver inflammation. It belongs to a class of medicines called nucleoside analogues, which work by inhibiting the reverse transcription process in the HBV replication cycle.
Mechanism of Action:
Entecavir is a guanosine nucleoside analogue that is converted intracellularly to its active form, which inhibits HBV polymerase, effectively blocking viral DNA synthesis and reducing viral load.
Key Benefits:
Suppresses HBV replication and slows progression of liver damage
Improves liver enzyme levels and reduces liver inflammation
Low risk of resistance with long-term use
Well-tolerated with once-daily oral dosing
Dosage & Administration:
The recommended dose is 0.5 mg once daily, taken on an empty stomach (at least 2 hours before or after a meal), or as directed by a physician. Dosage may vary based on liver function and treatment history.
Important Information:
Regular monitoring of HBV DNA levels and liver function tests is required
Not a cure for hepatitis B, but highly effective in long-term viral suppression
Use with caution in patients with renal impairment; dose adjustments may be necessary
Treatment should be initiated and monitored by a hepatologist or infectious disease specialist